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Elephant in room: Open Dyslexic is an Arts Project. No evidence it helps anyone (Dyslexic of ADHD), but there is evidence it is harder to read than simply increasing size.
Otherwise, there is no problem embedding a font as Karellen & DNSB write.
However some Android apps have no "publisher" font option. Conversion to azw3 will work, but four models of Kindle, (K1, K2, DX and DXG) can't be upgraded to azw3 and old mobi neither supports user added fonts or embedded fonts.
If the device has the font (either supplied or added by user in designated location), then the CSS is similar but the font doesn't need embedded.
There are periodical arguments about serif vs sans and it turns out it may be what ever you are used to works best. So if paperback fiction then serif such as Georgia or Times and if web pages and Apps then sans such as Arial or Verdana, or the Google/Android versions.
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