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Go ahead. Though it would be interesting to see how you compensate for font size and screen width since that will impact the amount of text per line. Remember that epub like any reflowable format does not have a defined page size, font size, line spacing, etc.
BTW, A quick search seemed to find no real evidence for your claim. Some seem to support it, others seem to find that it has from no substantive impact to actually having a negative impact.
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