Do you already know how you want to sync your Calibre library, as there are various options?
https://www.mobileread.com/forums/sh...&postcount=148
For example, I have a copy of my calibre library on my NAS and simply sync the metadata.db. When I want to read a book, I simply connect to the NAS and download it.
You could also just put your entire calibre folder on your mobile phone, then you would have the same folder structure.