I go edit only in odt, Save As (copy) as docx, convert to epub in Calibre.
Fix any issues with headings or images.
Convert the epub2 to dual mobi. Only four early models of Kindle need mobi. It's a terrible format. The dual mobi has original 2007 style mobi and the current azw3/KF8 (which is very similar to epub2, in fact there is an epub from azw3 extraction tool).
Generally no editing is needed. I only use the Calibre editor to do quick fix of <h tags (less than a minute for any size ebook) and CSS of image sizes, AND only for epub being uploaded to publish. Amazon takes epub, but not mobi/azw3/kfx for regular reflowable novels. Same file as works to publish anywhere else.
PDFs are direct from LO Writer, but changed styles.
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