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Yes, you can use Profiles.
1) There is an option to save all current settings to a Profile, in Top menu - Document Settings - Save current settings to a profile. So, you can tweak close to “publisher defaults” and save these settings to a Profile.
2) For all other “default” settings, you can always revert to them from the same Document settings sub-menu in Top menu.
3) To make a setting default, long-press on the setting, it will ask you to confirm. This works for many settings in Bottom menu, as well as Top menu.
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