XYZ brand ereader IS NOT the standard we design to.
EPUB designs are for 1 up devices, not 2 or 3 up. Not multi column.
ONE UP
Why, because whatever you do will not 100% work for any user front or any zoom level.
If you want to fudge.
1)chapter per file. That at least gives the viewer (app) a chance to start left
Or if you also put a (non printing) line in, then Pagebreak: always; if you want on right.
BUT
Not every viewer even honors all CSS commands (xyz developers
know better what you want.