See also the wiki here which lists apps:
https://wiki.mobileread.com/wiki/EPub_3
Quote:
Available Readers
Adobe Digital Editions version 4.0
AZARDI - for Windows, Macs, and Linux. Currently the best coverage
iBooks - for iOS devices. [Now Apple Books]
Kindle [app on] Fire - Spotty coverage using KF8
KITABOO - For ios, android, windows, mac, and online.
Readium™ is a project of the International Digital Publishing Forum (idpf) and supporters, is an open source reference system and rendering engine for EPUBŪ publications and is targeted at ePub 3. Currently this is an app for Google Chrome browsers
Lektz eBook reader - for Chrome browser, iOS, Android
Advanced ePub3 reader - from Helicon Books, only available for Android, iOS, and online.
Android reader open source.
Menestrello a free reader that supports media-overlays for simultaneous reading and listening to audio books. For iOS and Android.
Gitden Reader supports both flowing and fixed layout ePub. Available for iOS and Android.
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The iBooks - for iOS devices and Kindle app on Fire using KF8 likely only work well with ebooks from Apple or Amazon respectively.