It is not often that I read fiction on my PC. But it does happen.
Anyone reading on a PC should take a look on the
WordWeb program
It has the distinct feature that it can read the word under the mouse cursor with a hot key combination and then activate the program.
In the picture below I have activated the program by doing a ctrl + rightclick on the word "Cambridge".
You can now select to search for "Cambridge" using any dictionary tab.
The dictionary tabs can be user defined in the pro version.
I am not in any way affiliated with WordWeb.