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Of course the font face (metrics) and font size set a default line height on any sensible renderer so as descenders don't touch tallest item on line below.
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My concern for the typographical presentation goes a bit beyond whether ascenders and descenders touch. I am one of those mad people who believe in leading, since I added enough of it in sheet lead metal when setting letterpress books to come to believe that too much and too little are either side of just right.
Kindles are little better than a typewriter with single and double spacing, 1.5 if it's a good typewriter. I'm not trying to impress any leading decisions on a Kindle because it ignores them. But if a reader shows merit and finesse, like PocketBook Reader on Android, then why not cater for it with some CSS that is better than it can achieve on its own? It's not 'breaking' Kindles, and some other reader is hardly rendered completely useless by my decision.
But if line-height is little more than a choice between too tight and too spaced for you, then I can understand you not setting it and relying on the device to perhaps come up with something just bearable.