I do use Diap's Editing Toolbag to blow away a lot of the junk I don't need or want such as <section> with or without stuff in them. Change span italics/bold to <i>/<b>, but the <a> page numbers and a number of other things.
Once you know you don't need any IDs, blow them away too. One thing I find really interesting is how much smaller the ePub becomes once you've blown away all the junk the put it like all those <p class="uselessclass"> when you convert to just <p>.
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