You want nothing to do with serial port. If there is some crappy Qcom stuff there uninstall it.
Edit: You're showing "ADB interface" at the bottom there. Is that a separate device?
The PCI serial port there is some other piece of hardware on your PC that's malfunctioning.
I'm not sure how edl.exe found your device but couldn't open it, unless there are multiple interfaces. You ever use UsbView?
https://www.ftdichip.com/Support/Uti...crosoftUSBView
Then go find your Note Air 2 and look down the column "bNumInterfaces".
It should be one.
Are you logged on a regular account? It shouldn't have to be Admin, but it can't be some underpowered user.
Under UsbView it should look almost identical, 1 interface, 2 endpoints,
2 open pipes