I am not aware of any issues with the portable version. Did you link your Adobe ID account in the plugin settings?
If it still doesn't work, can you post a debug log? In Calibre, click the arrow next to the "Preferences" icon, then click "Restart in debug mode". After Calibre has restarted, delete the book again and re-import the ACSM, then close Calibre. A couple seconds later a text file should open with a bunch of logs.
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