In addition to theducks' comment, I Googled and downloaded a runic font and made a simple epub with the font embedded and a CSS that creates a class
The @font-face and the .runes are needed
Code:
@charset "utf-8";
/* Styles for Test */
@font-face {
font-family: "Angerthas Moria";
font-weight: normal;
font-style: normal;
font-stretch: normal;
src: url(../fonts/AngerthasMoria-lgLAD.ttf);
}
.runes {
font-family: Angerthas Moria;
font-weight: bold;
font-size: 1.5em;
}
HTH