I have moved Calibre (Libraries) between 5 different PC's (Win,Linux) since I joined MR. Only once, did I do something stupid and needed to recover from an older backup
I did copy my Config folder as part of the move and all I had to do was adjust the Path (Create/Switch: Use existing) to the new Library location.
OTOH Keeping Kindle Tools functioning
Over the years, I did slightly change how I tracked Series, but most custom column stuff dates back to Kiwidudes PI's first showing up