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Originally Posted by conan50
With Moderna in the US you get the same brand shot the 2nd time. Is it different for the 2nd shot in other countries?
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Here in British Columbia, Canada, it depends on what vaccine is available. Some people have received Moderna as their first shot and Pfizer as their second or vice versa. Those who received AstraZeneca as their first dose were given the option of Pfizer or Moderna as their second shot if they were worried about TTS.
According to various studies quoted by the health agencies, there seems to be no noticeable change in the protection offered by the mRNA vaccines regardless of mixing and matching. For an AstraZeneca first shot and a mRNA second shot, there is less data but it seems to indicate minimal changes in the protection offered.
For my second dose, I noticed a bit more soreness around the injection site compared to the first time but nothing debilitating.