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In my experience, the lights on some e-ink devices haven't been as bright as lcd devices, but they are migraine triggers too.
I also get halo effects around light bulbs, headlights, etc., and blurring around that. Probably astigmatism-related. Direct lighting usually involves a sharper contrast between the light and everything else than indirect lighting has between the lit area and everything else. Front lights for screens being a sort of middle ground there. So that could aggravate halo effects, pattern sensitivities, etc.
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