There's very encouraging news from a trial of a new malaria vaccine. It gave 77% protection. There's a bigger trial taking place to confirm the results, but this is excellent news.
https://www.bbc.co.uk/news/health-56858158
Malaria infects around 200 million and kills around 400,000 people
every year.
(For comparison, SARS-CoV-2 has infected around 150 million and killed around 3 million over the past year)
If this vaccines turns out to work as well as this result suggests, it could make a massive difference to the incidence of malaria.
This is not only because people will be directly protected against the disease by the vaccine, but because malaria requires mosquitos to have bitten an infected human before they can pass the parasite on to other humans. If the number of people infected with malaria drops, so will the transmission rate. If enough people are immune to the disease, we might wipe malaria out altogether.