I tried the same things with my AV disabled, but it made no difference.
All the tests were done without the use of the preview window (F10). I also have only one dictionary selected for spell checking.
Turning preview on further slows things down, to a point were even selecting menu entries gets slow on occasion.
I have also noticed that when I open both the title-page and chapter 12, just switching active windows gives a delay.
title-page > chapter 12 about 6s
chapter 12 > title page about 1s
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