[Tex2002ans]

Originally Posted by AlexH2021

Would I be right in saying that not all E-reader software can handle text colour?

Correct.

And like the others have said:

Don't rely on color alone. Make sure to use alternate methods of emphasis as well.

Originally Posted by AlexH2021

In Sigil I use this code;

Example - <span style="color:Crimson;"><b><i><u>North British House, Smeaton Road, Kirkcaldy</u></i></b></span>

Instead of hardcoding the color+bold+italics+underline every time...

Better to use CSS, like this:

HTML:

<strong class="crimson">North British House, Smeaton Road, Kirkcaldy</strong>

CSS:

strong.crimson {
	color: crimson;
}

This has multiple advantages:

1. The <strong> will still bold text on e-ink (and readers that override CSS).

2. This allows you to easily adjust the look of all the text in a single location—the CSS file.

Like JSWolf said, you might want to use a different font as well:

strong.crimson {
	color: crimson;
	font-family: sans-serif;
}

or you could still do your bold+italics:

strong.crimson {
	color: crimson;
	font-style: italic;
}