E-ink is a godsend! My eyes get tired sitting in front of a computer screen for big chunks of my day and reading on an active screen for more than a couple of minutes is torture.
I feel today's e-ink is almost as good as paper. I couldn't do without it since I move around a lot and can't take my library of physical books with me; and I refuse to read on a normal screen (I have done so in the past, and my eyes were sure to punish me for it). I also read in several different languages, so an e-reader makes it easier to gain access to the books I want to read; they are often not available in physical copies or crazily expensive. The built-in dictionary also helps - I remember hauling around a big dictionary whenever I read a book before.
Whenever I find myself a more permanent place to live I will prefer physical books for everything except language learning, traveling and the books I can't easily buy other than electronically.
For me the future of e-ink lies in another direction, though: in higher refresh rates and colour screens.
I look forward to the day when I can buy an affordable e-ink monitor for my computer with a high enough refresh rate to allow writing without visible lag. The other thing I'd really want is a 13 inch colour ereader for graphical novels and comics. Oh, and a black and white e-ink phone. Then I'd be all set