if you need epub3 you either need a PDF or an App. Only epub2 is assured of working on all epub apps and ereaders and is also still the best format to upload to Amazon KDP.
While it's technically possible to have text at the bottom of a page, you are better not trying to duplicate the exact appearance of paper books.
Avoid
Drop caps or images with text flowing round them
Clever formatting to have text at the bottom of a page.
Colour
Links without underlines
Underlines that are not links (on typewriters it meant set this in bold)
Oblique text rather than using an Italic font.
SMALL CAPS. Simply having a smaller font looks poor, though works sometimes.
Animation, transparency, video, audio or interactive. Pretend it's paper. Put a link and a QR code to the media on the Web or in an App.
Other issues.
If the book is for a Western Latin/Roman font audience then avoid Cyrillic, full Greek (there is limited support), Arabic, Hebrew, any Asian font, emojis, vertical text or right to left text. Those are all possible, but on a subset of eink models, often for a particular market and also app etc for those markets. Curiously Icelandic and Polish characters seem to work on quite old Kindles, but not the full modern Greek alphabet. Embedding an image of an unsupported word works really badly. There are transliteration rules for Russian Cyrillic and Chinese (pinyan). Hebrew and Arabic are commonly transliterated to English even on supermarket products.
Check on a variety of old ereaders if in doubt.
Update of devices:
Many can't be due to lack of RAM. Or the people that wrote it are gone. Also no assurance that users will update.
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