[phillipgessert]

I could see underlining a book's title if it appears within an italicized blockquote. I'm not dead sure whether the usual approach of reverting to roman text is suitable in that context.

ETA, my vote is to use proper primes as it seems impossible to account for every font. By which I mean a user using a very flexible e-reader app could hypothetically choose a
homemade font that doesn’t even include proper curly quotes. So, being impossible to entirely avoid an ugly fallback, better to just code the intended.