Too much contrast is harsh. I prefer the lowest contrast possible that fulfills the need to read comfortably. Granted - the more contrast you have, the sharper things appear. But that's not always a good thing. Excessive brightness is just as bad. Who wants to stare into a spotlight? Ditto for excessive whiteness (higher color temperature).
I agree with JSWolf on the software aspects. I do enjoy using Moon+, from a feature point of view. Moon+ clearly beats a Kindle in the feature department, but the Kindle with it's eInk screen beats Moon+ in the eye comfort department. Although, once I get Moon+ set up the way I like it, I pretty much only use page turning and simple navigation. Sometimes font resizing when my eyes get tired. That's why, given a choice, I will always choose my Kindle PW3 over my tablet with Moon+ if both are available to me (except when reading PDF's).
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