Hmmm, BetterRed, that gave me an idea. Maybe I can make a duplicate of the file in Calibre Library, rename it, and bring it into Calibre as a new book. Then see if it would keep my changes after that. I'll report back later.
(I only fiddled with the metadata after I failed to locate my edited file. I also tried to save a copy under a different title, but that didn't solve my problem either.)
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