Thanks for the replies and trying to help out.
This is going to remain a mystery I'm afraid. An entire directory on my PC moved to a location where I was saving a download of a pdf from a link. The directory that magically moved itself? Roaming/Application Data! The contents of which contain most all of the personal configurations of every application on the machine. I searched for info on how this might have happened; did every conceivable security check; I found nothing conclusive. Strange disembodied beings apparently decided to mess with me. Once I figured out how to copy that directory back to its rightful place (and merge into the reinstalled configuration of Calibre) my personalizations were back intact.
Thanks again. This thread can be closed!
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