If the book already has a chapter heading with some unique style, there is no problem using the split at multiple locations tool. Even if there is some searchable way of finding such split points, it is easy to use regex S&R to put in splitable code, like looking for <p>"CHAPTER something"</p> and changing the <p> to <p class="chapter">, then using the split tool on that.
But if I have to search through the document for split points, it is easier to just split the file manually, using the preview pane tool, as I go through it to find the boundaries. This also has the advantage of letting me spot rocks I might miss trying a more automated approach.
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