The last time I was browsing through a battery manufacturer's website, their published test results showed their lithium-ion batteries were good for ~650 full charge cycles before the battery capacity dropped to 70% of the original capacity (there are dependencies on environmental conditions such as temperature and very bad ideas such as overcharging). One of the chart showed the life cycle for various depths of discharge which basically showed that shallower discharges allowed more discharge/charge cycles (a 50% charge cycle giving about 2400 cycles). So if you read enough each day to result in 50% battery use and plug your ereader into a charger when you go to bed you should get around 6 years before the battery reaches EOL.
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