the other approach is to accept that the reader will select the font, not the author. both kindles and Kobo devices offer 6 or more fonts which you can select using the device menus( plus it is not hard to add fonts to the device, which all books can then access)
all that the book has to do is NOT try to enforce a font, so that the reader device can take control
( same goes for line heights, margins, justification )
can't speak for i phones, don't have one... but the apple philosophy is all users are idiots, lock everything down... so forcing any font to show up on an apple device may be problematic.
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