from what I have read in various places. keep it between 40% and 90% for best longevity
going to zero is bad, and charging to 100% is not necessary, that final 2 -3 % of charge does more harm than good
but even if you disregard all advice, the battery well probably last until you decide to get a newer model, as a Kindle needs far less charge cycles per year than a smart phone
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