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					Originally Posted by  binaryhermit
					 
				 
				But that's an extreme corner case, to the point where anyone in that situation probably has a way to interface with the rest of the world such as using Calibre for conversion 
			
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 Exactly.
MOBI/KF8 works in all Kindle readers.
EPUB works in all non-Kindle readers.
PDF works on PC (and wherever else you want to read that). (In the case of Non-Fiction, many tend to prefer this format for citations.)
HTML works everywhere you have a browser...
and anything else can be converted on a case-by-case basis from one of those formats (EPUB is what I prefer as source).