Quote:
Originally Posted by JSWolf
Check the permissions for drive D:. Also try running Calibre as administrator and see if that works. If Calibre works when run as administrator, then it is the permissions that need fixing.
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A permissions problem wouldn't cause an I/O error message, and it wouldn't cause the USB D: drive to work at all times when not being used by Calibre. This error is only being generated when using Calibre. Also, whether being run as an Administrator or not wouldn't make a difference in the problem that results in an I/O error.