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Dyslexic readers I have spoken with overwhelmingly prefer sans-serif fonts, and actually quite a few of them prefer Comic Sans MS even though designers despise it.
I'm not dyslexic but my eyes are not as good as many people.
I know they say to use Sans for headers, Serif for content - but I find it more readable to use Sans for both.
I usually use Helvetica Bold for headers (section titles) in LaTeX and either Clear Sans or Lucida Sans for content - but my Helvetica (and my Lucica Sans) licenses only cover Type 1 .pfb
Specify Helvetica w/o including it, and many will use Arial which is definitely not as pleasant to look at for section titles. Liberation Sans though is metric compatible w/ Helvetica and looks very good.
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