One big difference is that I compress images with k2pdfopt, but due to various bugs, I no longer compress images with ghostscript. If image compression is the biggest difference, then
(1) I can compare the sizes of
(compressed) k2pdfopt -ui -mode copy -dev dx -o %_k2opt\ dx
with
(uncompressed) k2pdfopt -ui -mode copy -o %_k2opt\ copy
using the relative sizes as a rough proxy for the relative delays. But I've got some with a 4.0:1 ratio and no trouble, and others with a 2.4:1 ratio and freezes.
(2) I can use
(uncompressed) k2pdfopt -ui -mode copy -p 1-10 -o %_k2opt\ test
using the sizes as a rough proxy for the delays. But I've got some freeze-prone files at the 2.2 MB range and tolerably fast ones at 4.4 MB.
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