And for the OP, using epub format, if the publisher has set up the embedded font properly, it won't matter what font is selected on the Aa menu as it will be overridden by the epub style. Several ebooks I've read have an an embedded font used for special items (chapter headers are the most common) and it doesn't matter what font I select, the chapter header used the embedded font.
OTOH, too many ebooks use fonts that are not available or use simple serif and san-serif which makes it a pain to select another font.
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