You could add Calibre to your Startup folder, C:\users\<yourname>\appdata\roaming\microsoft\wind ows\start menu\programs\startup (good grief, I can't believe I actually found it). First find the Calibre .exe file, right click on it and select Copy, then go into the Startup folder and do Paste Shortcut (
NOT Paste), then right click on the shortcut you just created and select Properties, select the Shortcut tab, in that in the Run box select Minimized. That's what I do for Mozilla Thunderbird; here's its (the shortcut) Properties box on my computer with that: