If you're older and it hasn't started yet, watch out for Presbyopia. I.e., can't focus close and need reading glasses. It caught me by surprise; I think I was in my late 40s or early 50s.
Anyhow, the point being that when you do start needing reading glasses you may also find it more comfortable to increase the size of the text on the screen. Which makes the lines shorter and which annoyed me to no end with my 6 inch screen Kindle Touch.
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