I'm in your position: I need to read and annotate a shed-load of academic PDFs. Take my advice and buy a tablet, not an eInk device. PDFs need a fast CPU and lots of RAM. eInk devices are optimised for long battery life and have (compared with decent tablets) slow CPUs and relatively little RAM.
The best solution for reading and annotating PDFs is, to my mind, an iPad with the "GoodReader" app. Superb app - the best PDF reader on any platform, to my mind.
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