Question for long-time Kindle and Calibre pros: When you upload your own non-DRM books to the Kindle Cloud, what are the main limitations in feature support (in contrast to books that you buy directly from Amazon and used in their DRM'd form on your devices)?

Here are the limitations I found, trying this recently:
* Uploaded non-DRM'd books--even if bought originally from Amazon--go into a special folder in your Kindle account called 'docs'. The books in this collection are treated differently from your normal Kindle ebooks that are in their original format and DRM'd.
* Your uploaded books, although they do benefit from storage in Amazon's cloud, will only sync the book and the reading data (positions/notes/highlights) across Android, Kindle, iOS, or Mac devices; they will NOT sync to PC, nor to your "Cloud Reader" Kindle account.
* Your uploaded books do not have their reading notes rendered in the online Kindle notebook at read.amazon.com/notebook. This is a great feature that I'd find useful, so it's a bummer to learn it's limited to Amazon Kindle DRM'd books.
* Uploaded books do not get rendered in the Amazon Cloud Reader. Another option that's nice as it gives browser-based access to your books from PC, Mac, or Linux, without needing to install an app.

Are there other significant limitations for uploaded books?