The issue I had with FileTypesMan revolved around its support for user maintenance of Verbs in the Explorer context menu - Print, Edit, Twist, Flip, whatever. I have a suspicion the API to add/remove Verbs to the Explorer context menu may have changed at some stage - Vista would be my guess. Providing you take a system checkpoint before using FileTypesMan, or anything like it, you should be able to restore should anything go awry.
Workaround - put shortcuts to the programs you want in your send to folder (Win+R shell:sendto), force them to the top of list by prefixing the shortcut names with a bang.
BR
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