To install ADE 2.0.1 on Linux follow the instructions on our own Wiki, which have been recently updated:
https://wiki.mobileread.com/wiki/ADE_2.0.1_Linux
If it doesn't work for you then there are a number of us on Mobileread who have taken an interest in the matter and are happy to help. The link posted earlier to Pat David's blog is good and should work. Pat based this on the Mobileread Wiki instructions which he had to modify slightly to deal with some problems installing on Ubuntu. The Wiki has in turn been updated to incorporate his work. This is the beauty of Open Source.
Cloud library does not need ADE. It uses Adobe but the software itself handles the fulfilment. It works under Wine. Later versions of ADE do work under wine, though it is broken with the last few minor releases. I can't recall exact versions but you can get the latest version working on wine with Winetricks. Just replace the binary winetricks downloads to its own directory under ~/.cache/winetricks with an earlier minor version which will install. I think the latest .0 minor release works. The latest minor releases will not install under Wine as the installer thinks that the binary is already running.
My current Linux install has working versions of K4PC, ADE 2.0.1, Cloud Library, Kobo Desktop and Overdrive for Windows. I have modified my Kobo Desktop setup to integrate properly with the Obok Calibre Plugin. Basically everything I want is currently working,albeit with a little effort along the way.