Over time, I've had so much trouble with this on my Kindles that now whenever I edit a book, I just take out all the fonts and references to them. I have a saved regex search that finds "font-family.*?;" and replaces it with nothing in all style files.
Once in a while, if a book contains a bunch code or typewriter text or something, I will allow a "font-family: sans-serif;" line, and the Kindle seems OK with that.
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