If you drag-drop the amended ebook-file (EPUB, PDF, MOBI, whatever) into the relevant Book Details panel (right sidebar) it will replace the existing file.
But, I'm not sure that all e-reader devices/programs embed annotations etc within the ebook-file itself, I believe some create separate files, commonly known as sidecar, companion, or buddy files. So, what format and what device/program do you use?
BR
Last edited by BetterRed; 06-01-2018 at 01:23 AM.
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