Firstly thank you to all of you who have replied and tried to assist.
The issue is definitely not a failing hard drive. The library is stored on a partitioned separate internal hard drive from the operating system and I have no issues in accessing any other programs/data on that partition. However to be sure I re-installed the library on a third internal drive with similar startup times.
Once Calibre has loaded and I close it, I can re-open it in a matter of seconds without any sounds of the drive 'seeking' information. However if I reboot the computer then the drive can clearly be heard as it seeks something?
Searching for files - rebuilding a cache? who knows.
As can clearly be seen I am no expert in how Calibre works so wondered if there is a cache somewhere that is being deleted on shutting down the computer and which needs to be rebuilt on boot up?
Or if there is a cache has it been created in a separate location and is affected by the re-boot?
As it stand it seems I must simply wait for Calibre to load and be patient.
Thanks to all
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