Aha, I think I found the problem. IIRC, the 64-bit Calibre had a problem saving files ("Save files to disc" in the library manager), which was apparently a known issue when also using SpiderOak, so I uninstalled and installed the 32-bit version, which I've been using ever since. But the registry was full of calibre64XXX keys which hadn't been removed by the uninstaller, so I deleted those (well, the ones I noticed, anyway; there were lots of them...) and all is now well.
Thanks everyone!
Last edited by Phssthpok; 08-11-2017 at 10:55 AM.
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