Sure, why not? I already read plenty of episodic fiction with no clear end point*. It might even be a nice change, for once.
Actually, it's not so bad if the episodes really are that: reasonably self-contained with a a start and end mini-arc inside which resolves at least one character or plot point and thus tells a complete story about that within the greater eventual whole.
The ones that are just strung-out snippet chapters which advance the plot piece-by-piece without resolving anything until the very end are kind of annoying (stupid sexy decompression), but would be acceptable if they had a clear start and endpoint and overall plan to their storytelling arc. I wouldn't pay much for those, mind you, and would probably wait for a collected edition anyway.
* North American superhero comics, as one might expect, but also those assorted novel series that the author abandoned ages ago (or just plain died in the middle of) on a cliffhanger and/or have been promising the next installment of Real Soon Now. For over a decade…