I've had a Cybook (I broke it) and then I bought an iLiad Book ed.
I like the larger screen of the iLiad and the flipbar, but it's also over twice as heavy and it feels a little cumbersome to sit and hold it for a long time compared to the Cybook. One thing I didn't like about the Cybook is the page turn button, it's put in an awkward place and the flipbar on the iLiad is much superior.
With regards to file formats, Cybook is probably the best there is for mobi/prc. It's not very good for HTML (for instance it can't handle tables so downloaded web pages often didn't look good) and I found it crashed often with PFDs.
I read a lot of fiction off the Internet (often fan fiction) and for that purpose the Cybook wasn't especially good. Mobipocket files created from saved web pages didn't work well becuase the original HTML formatting often weren't up any standards, and then I tried creating PDFs based on Word files, and they looked okay, but it crashed about once every hour or two.
That's why I bought the iLiad. You can install a developer package and install your own applications for instance. The native support of mobipocket on the iLiad is far below Cybook, but it has good support of PDFs. The native browser on the iLiad didn't meet my needs, and I would have had to install a different one. I've actually never gotten further than creating custom sized PDFs, but it's easy and it fits my needs well.
It's a lot easier to install your own fonts on the Cybook than the iLiad.
The iLiad has folder support, which the Cybook doesn't.
As you may guess, what you need it for, what you want to read on it, is an important issue. Size isn't much of an issue compared to this. I've actually been thinking about getting a BeBook because I think the iLiad really is a bit too large and heavy for ease of use and portability.
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