As per your suggestion, I have terminated Sticky Password, and to my surprize, Calibre didn't freeze (yet) which is a very good start. I opened it without Admin rights and at the moment, it seems to run fine (hopefully it will continue to). Right now I am using Calibre portable which is only x86, but I will install the x64 version, give it a test, and come back with the results.
This issue has driven me mad ever since the Anniversary update, and I truly hope that I've finally found the culprit. If so, I'm gonna write to the Sticky Password team and let them know this issue so that they can fix this bug.
Thank you all for your suggestions, much appreciated!
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