'Passport' is an external USB3 (2.0 compatible) drive, not a NAS so she is good to go.
I do second install 'Portable" for use when away from your
home base equipment. You can still use the same Libraries with Installed Calibre

Use the OS Disk Management tool to assign a single drive letter (I use L:

) so you can start desktop Calibre, knowing the Library path will always be the same no matter which USB port you attach the drive to