Musicbee understands audiobooks, I've rather fallen for it and use it for all my music and audio now. Out of the box, if you add audiobooks to the Audiobook library it treats them differently when you play them, such as remembering position, turning off any shuffle/repeat settings from when you were playing music, etc) It's also one of the few players outside Itunes that understands the chapter markers properly in m4b formatted books. From there you can use a custom tag (similar to custom columns n calibre) to keep series labelled and together etc.
It's a bit calibre-like in the amount of customisation you can do, which makes it a bit intimidating to get started with, but once you have it set up to your satisfaction it's very nice. Since you mention failing eyesight, there's also a ton of customisation in the visual layout too, which you might find useful.
As far as the initial topic, it'll either calibre/iTunes style organise the files for you, or not, your choice.
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