@sbin:
If you use a roll-your-own native "SQL Query" using the Multi-Column Search plug-in, I believe so.
https://www.mobileread.com/forums/sho...d.php?t=261712
For an example of what I am referring to, see the attached image.
If you know SQL, the example SQL code in the SQL Query Tab plus that Tab's ToolTips should tell you what you need to know.
If you don't know SQL, I might have time to write the SQL Query for you after tomorrow (Diwali parties are more fun than writing SQL). If so, I will post a template for you to copy-and-change per your specific Custom Column names.
Note that the options "Final Filters" and "All Author's Books" may also be specified to be applied after the SQL Query executes but before the results are shown to you.
DaltonST